Raptim Research

Sr. No.	Drug Name	Assay	Linearity Range	Matrix	Instrument
1	Buspirone	Caco-2	0.0050 µM to 1.0099 µM	HBSS Buffer	API-4000
		GI Stab	5.0163 μM to 50.1228 μM	SGF and SIF Buffer	API-4000
		Solubility	0.5020 mg/mL to 40.1577 mg/mL	Buffer media	API-2000
2	Doxepin	Caco-2	0.0010µM to 3.0046 µM	HBSS Buffer	API 4500
		GI Stab	0.0050 mg/mL to 1. 9984 mg/mL	SGF and SIF Buffer	API 2000
3	Levorphanol Tartrate	Caco-2	0.0051 µM to 5.0070 µM	HBSS Buffer	API-3500
		GI Stab	1.0192 µM to 101.1060 µM	SGF and SIF Buffer	API-3500
		Solubility	1.0192 µM to 101.1060 µM	Buffer media	API-3500
4	Imatinib	Caco-2	0.1052μM/mL to 29.5504μM/mL	HEPES Buffer in HBSS	API 4500
		GI Stab	10.0074 µM/mL to 501.2200 µM/mL	SGF and SIF Buffer	API 4000
5	Dexamphetamine	Caco-2	0.1499 μM/mL to 174.5929 μM/mL	HBSS Buffer	API 4500
6	Varenicline Tartrate	Caco-2	0.0030 μM to 2.9768 μM	HBSS Buffer	API 4500
		GI Stab	0.0010 mg/mL to 1.0011 mg/mL	SGF and SIF Buffer	API 2000
		Solubility	0.0010 mg/mL to 1.0011 mg/mL	Buffer media	API 2000
7	Ramelteon	Caco-2	0.0113 µM to 5.0188 µM	HBSS Buffer	API-3500
		Solubility	10.0074 µM to 501.2200 µM	Buffer media	API-3500
8	Valbenazine	Caco-2	0.0208 µM to 73.3549 µM	2mM HEPES Buffer in HBSS buffer	API-4500
	ɑ-dihydrotetrabenazine		0.0117 µM to 41.1459 µM
9	Pimavanserin Tartrate	Caco-2	0.0039 µM to 4.5578 µM	1 % BSA in HBSS Buffer	API 4500
10	Cyclophosphamide	Caco-2	0.0200 µM to 50.5086 µM	HBSS Buffer	API 4500
		Solubility	0.0111 mg/mL to 1.1004 mg/mL	Buffer media	API 3500
11	Hydroxychloroquine Sulfate	Caco-2	0.0250 μM to 10.0397 μM	HBSS Buffer	API 4500
		GI Stab	0.1003 mg/mL to 10.0489 mg/mL	SGF and SIF Buffer	API 4500
		Solubility	0.1003 mg/mL to 10.0489 mg/mL	Buffer media	API 4500
12	Brivaracetam	Caco-2	0.1314 µM to 942.1759 µM	HBSS Buffer	API 3500
		GI Stab	0.0104 mg/mL to 1. 0220 mg/mL	SGF and SIF Buffer	API 3500
13	Amitriptyline hydrochloride	Caco-2	0.1029 µM to 64.1001 µM	1% BSA in HBSS Buffer	API-4500
14	Guanfacine hydrochloride	Caco-2	0.0010 µM to 2.5607 µM	HBSS Buffer	API-4500
15	Cevimeline	Caco-2 (i3 pharma)	0.0050 µM to 10.0495 µM	HBSS Buffer	API-4500
16	Dicyclomine	Caco-2	0.0215 µM to 25.1946 µM	1% BSA in HBSS Buffer	API-4500
17	Capecitabine	Caco-2	0.0202 µM to 10.0788 µM	HBSS Buffer	API-4000
		GI Stab	236.9059 μM to 9225.3932 μM	SIF Buffer	API-4000
		Solubility	0.0251 mg/mL to 2.0048 mg/mL	Buffer media	API-4000
18	Propranolol hydrochloride	Caco-2	0.0205 µM to 20.1545 µM	HBSS Buffer	API-4000
		GI Stab	101.8333 μM to 1503.2541 μM	SGF and SIF Buffer	API-4000
		Solubility	0.0250 mg/mL to 0.4002 mg/mL	Buffer media	API-4000
19	Lormetazepam	Caco-2	0.0010 µM to 0.2097 µM	HBSS Buffer	API-4500
		GI Stab	1.2392 µM to 20.0634 µM	SGF and SIF Buffer	API-4000
20	Migalastat hydrochloride	Caco-2	0.0010 µM to 0.2580 µM	HBSS Buffer	API-4500
21	Solriamfetol Hydrochloride	Caco-2	of 0.0053 µM to 1.0539 µM	Methanol : Milli-Q water	API-4000
		GI Stab	15.1247 μM to 609.5724 μM	SGF and SIF Buffer	API-4000
22	Lofexidine Hydrochloride	Caco-2	0.1016 nM to 20.3288 nM	HBSS Buffer	API-4500
		GI Stab	50.3205 nM to 603.8458 nM	SGF and SIF Buffer	API-4000
		Solubility	0.0136 mg/mL to 0.2630 mg/mL	Buffer media	API-4000